Bless the Children operates a children's home in Guyana, a developing country in South America. Because of political and economic issues, the country has more than 200,000 children living in extreme poverty.

Bless the Children provides accommodations for as many as 40 children and the home’s directors. The organization's other services include nutrition and spiritual care. The children attend public school nearby. If they need medical care, they go to a local hospital.

Philanthropists fund the children's home. To support Bless the Children in Guyana, donors can donate by credit card or wire transfer to the home’s bank account. Details are available at soworldwide.org/guyana-bless-the-children. Visitors can donate one time or set up recurring payments. The home also accepts offline donations. Bless the Children uses 100 percent of its proceeds to provide shelter, nutrition, health, education, and spiritual care to children.

As of March 2024, the children's home in Guyana is seeking $5,000 for a commercial stove and $4,000 for a commercial washer and dryer.